Age-Specific Serum Anti-Mullerian Hormone and Follicle Stimulating Hormone Concentrations in Infertile Iranian Women
نویسندگان
چکیده مقاله:
Background Anti-Müllerian hormone (AMH) is secreted by the granulosa cells of growing follicles during the primary to large antral follicle stages. Abnormal levels of AMH and follicle stimulating hormone (FSH) may indicate a woman’s diminished ability or inability to conceive. Our aim is to investigate the changes in serum AMH and FSH concentrations at different age groups and its correlation with ovarian reserves in infertile women. MaterialsAndMethods This cross-sectional study analyzed serum AMH and FSH levels from 197 infertile women and 176 healthy controls, whose mean ages were 19-47 years. Sample collection was performed by random sampling and analyzed with SPSS version 16 software. Results There were significantly lower mean serum AMH levels among infertile women compared to the control group. The mean AMH serum levels from different ages of infertile and control group (fertile women) decreased with increasing age. However, this reduction was greater in the infertile group. The mean FSH serum levels of infertile women were significantly higher than the control group. Mean serum FSH levels consistently increased with increasing age in infertile women; however mean luteinizing hormone (LH) levels were not consistent. Conclusion We have observed increased FSH levels and decreased AMH levels with increasing age in women from 19 to 47 years of age. Assessments of AMH and FSH levels in combination with female age can help in predicting ovarian reserve in infertile women.
منابع مشابه
Age-Specific Serum Anti-Mullerian Hormone and Follicle Stimulating Hormone Concentrations in Infertile Iranian Women
BACKGROUND Anti-Müllerian hormone (AMH) is secreted by the granulosa cells of growing follicles during the primary to large antral follicle stages. Abnormal levels of AMH and follicle stimulating hormone (FSH) may indicate a woman's diminished ability or inability to conceive. Our aim is to investigate the changes in serum AMH and FSH concentrations at different age groups and its correlation w...
متن کاملage-specific serum anti-mullerian hormone and follicle stimulating hormone concentrations in infertile iranian women
background: anti-müllerian hormone (amh) is secreted by the granulosa cells of growing follicles during the primary to large antral follicle stages. abnormal levels of amh and follicle stimulating hormone (fsh) may indicate a woman’s diminished ability or inability to conceive. our aim is to investigate the changes in serum amh and fsh concentrations at different age groups and its correlation ...
متن کاملThe Correlations of Anti-Mullerian Hormone, Follicle-Stimulating Hormone and Antral Follicle Count in Different Age Groups of Infertile Women
متن کامل
Follicle Stimulating Hormone and Anti-Mullerian Hormone Among Fertile and Infertile Women in Ile-ife, Nigeria: is There a Difference?
Background Reduced ovarian reserve has been known to predict poor ovarian response and poor success rates in infertile women undergoing assisted reproductive technology. Ovarian reserve also decreases with age but the rate of decline defers from a woman to another. The aim of this study was to detect any difference in ovarian reserve as measured by basal serum FSH and AMH between matched cohort...
متن کاملThe Correlations of Anti-Mullerian Hormone, Follicle-Stimulating Hormone and Antral Follicle Count in Different Age Groups of Infertile Women
BACKGROUND The objective of our study was to identify the correlations between the tests currently used in ovarian reserve assessment: anti-Mullerian hormone (AMH), follicle stimulating hormone (FSH) and antral follicle count (AFC) and to distinguish the most reliable markers for ovarian reserve in order to select an adequate strategy for the initial stages of infertility treatment. MATERIALS...
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عنوان ژورنال
دوره 9 شماره 1
صفحات 27- 32
تاریخ انتشار 2015-04-01
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